Great, or so I thought. She was refusing to eat out of her bowl which was a red flag because our cocker spaniel is OBSESSEd with food ( I think she likes food more than she likes us ?). E-mail: rfisher1951@yahoo.com The first day I thought he had something stuck in his throat but since then it hasnt stopped so here I am I decided to look up the side effects and found this site. BELLA. I noticed that he seemed a little lethargic after the first pill, but didnt feel alarmed since its supposed to do that. Stopped giving it to her and in 48 hours, she is spunky again. He has a low platelet count. He also had diarrhea and itching. This is how hydroxyzine is used on humans. It would be easier or me to inject her with something than get her to eat EFAs, probiotics, or administer colostrom. Although there is no way of knowing for certain if the drug Apoquel is responsible for what I am seeing with my dog, I am going to stop the drug altogether. Can Humans take Apoquel? I have never seen him like that so I wont be giving him the medication anymore. They say it can take a month per year of your pets life to work. As a result, hydroxyzine pamoate is what doctors will prescribe to human patients to treat anxiety. The patent on the drug does not expire until 2026, so we won't be seeing any generic Apoquel alternatives in the immediate future. But it is not the only antihistamine that vets use. My dog is much worse now and has a tumor under her forearm. I have also found that by wiping his feet with a damp towel after he comes in from outside, there is far less itching and scratching. We again returned to the center on April 30, 2018 to evaluate but left only with another prescription for Apoquel for $138.60. Bit worried about that. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. He has food allergy tests done several years ago and is allergic to rice, peas, carrots and several other things. However, he also developed skin growths right around that time and they will not go away. Can Dogs Take Hydroxyzine? Brief in length, 5 minutes. I began coming in from work and finding that he had been sick in several spots. Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. He cant come down the stairs or jump on the bed. She is supposed to go from 2 to 1 a day in 3 days. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. He is still on hepaticlear..3 years later. Apoquel should be given orally to your dog as a pill twice daily for the first 14 days, then reduced to once daily for maintenance. When I looked them up I immediately stopped the drug but it was too late. Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs. Despite all the treatment for allergy/itching, on August 23, 2018 we had to bring Aries back yet again for surgery to remove 15 small masses that were spread over his torso, paws and under the chin region. I am planning on trying to wean him off the Apoquel as soon as I feel he is stable. I have a 5 yr old Yorkie/Poodle. Apoquel works for most pets but not all. Lets have a look at how hydroxyzine is used to treat dogs. Even if a dog does not show immediate symptoms that are visually seen, I feel that internal immune system suppression and damage are occurring unseen and potentially will cause issues in the future that some dogs will not be able to be recovered from. He has symptoms of Cushings from longterm use of the Pred and he has a heart murmur. Hello, I have 2 german shepherds. Apoquel cannot be used for dogs under one year or breeding, pregnant, or lactating . Quite a misleading article. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. Fuck this drug. Normal is 2.5 4.3. I have found others not just on this web site that are questioning the same thing. Please share your comments. I decided to look up the side effects of Apoquel, as that was the only thing that was new and I wondered if GI upset and diarrhea could become an issue while on it. In one long term study published by Apoquel's manufacturer Zoetis, they studied 247 dogs over the course of two years. The other option would have probably would have been a lot worse. Your dog can continue to be treated with Apoquel as long as your veterinarian recommends. One studyfound that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably. Is it okay to take her off immediately, or do I need to wean her gradually? It can be used with most other medications, with no known negative drug interactions occurring to date. Her creatinine went from 8.0 to 0.3 almost normal!! I dont trust drugs and I dont trust doctors, or car sales men, or lawyers for that matter. Euthanasia 12-5-2017. This is for Denise Cunningham. I am taking him off of apoquell immediately. Kind of mad at my vet that they were so casual about giving it to her again. Your dog can continue to be treated with Apoquel as long as your veterinarian recommends. Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. Some of the horror stories above are frightening. My 15 year old Cairn developed environmental allergies when she moved to CT from FL. The mechanism of action is thought to be similar to that of other Janus kinase inhibitors, which block the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response, she says. I fear he may die! Carprofen was previously used in human medicine for over 10 years (1985-1995). I talked with a Homeopathic vet about my dog and this med and she said that she is seeing at least 4 dogs a week that are coming to her because of reactions to APOQUEL. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. with all I am reading, I am not sure if I will continue her on it or not. I searched apparel and found that this was a side affect. Treating dogs with antihistamines can take some trial and error as each animal reacts very differently. Your article leads people like Lynn with the yorkie to jump to blaming Apoquel for her dogs health issues with nothing to substantiate her claim. He had been on it continually for about two/three years as I was I informed that there was no serious side effects and that it could be used for as long as it was working. Low numbers of dogs in the studies developed demodicosis, neoplasia, pneumonia, bloody diarrhea, skin and ear infections . The vet put her on apaquel for 4 months. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. Now, in the last couple of weeks.. of going to Vet attempting to find out what is going on she actually bit a tech who stuck her face in Fendis face and startled her. But I love my dogs and if this is what happens with using Apoquel. We take a look at some of the most commonly asked questions about this drug. 2 days ago, on daily dosing st this point, he had another. I supplement benedry to keep the itching controllable at night. The itching and the lick granuloma healed. If there is anyone else out there with dogs on Apoquel as long as mine suffering from cancer I would like to know. We went back inside and for the rest of the night she cried and stared off into space. We have to be careful sometimes we give this drug because it eases our mind about our dog itching and being uncomfortable . The vet recommended Apoquel new improved antihistamine drug. Bloods came back as normal and vet said it wasnt the Apoquel that caused the fits. This is really scary.. because it is as though someone flipped a switch and she is just not herself anymore. Early this morning he got out of bed, I thought he was getting a drink, he has always drank a lot of water. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. My miniature schnauzer had the uncontrollable itchiness and smell that went with it. She ended up on 2 antibiotics and eye drop for 3-4 weeks. Do I Have to Stop Minoxidil Before Hair Transplant? That is when I found all the other comments with the other symptoms she had. Yes, it stopped his itching but at what price? In fact, antihistamines are quite often used to treat skin allergies in dogs. But what is hydroxyzine for dogs? She is licking herself just as much as she did before and she get some kind of black spots on her body, and her skin is full of small scales of dried skin which she never had before. Within a day he began acting different lethargic and mildly aggressive but he never stopped itching. She said if he was human, they would say he was anorexic. She is allergic to beef, flax, white potatoe, corn and a few other things. As I write this my 4 month old puppy is in ICU getting I.V. Drugs that suppress the immune system Hes been to Cornell, and we have tried just about everything. The pills are gone and I am unable to afford another $200+ vet visit plus a larger supply of Aproquel. Nothing processed, out of a can or a bag, no dry food ever (its basically rubbish anyhow). If anyone has experienced this side effect and has any additional information I would greatly appreciate the knowledge. The most horrible thing I was witness to.His right eye sunk in to his skull. But I dont know if 30 days is enough. stand up hes so weak. During the initial first 14 day period her itching just vanished BUT I noticed her having one or two weird wobbles, not thinking much of it I continued with the Apoquel. Kelly would love to know what your experience was. One of my boys had a Itching and licking had gotten worse. I only hope my baby Stoney will be Ok. Sick part about it is I believe they make this drug for people too. Hell no, healthy dogs mean less business. 7.The last increasingly used ingredient for allergies is colostrum. But it doesnt seem to work as well anymore. Anyone else having these issues? It comes in tablet form and is given daily, providing relief for 24 hours. Better safe than sorry. He has intermittent hotspots and a rash. I pray that there was no long term damage done. Hi. associated with allergic dermatitis and for the control of atopic dermatitis. Thats why I blame Apoquel. See what it can do for your dog here: http://www.thedogsupplement.com. I wish I could turn back time because I have caused permanent damage to my dog, and I am heartbroken over it. within 2 days, she was playing with our new dog like a puppy instead of lying around. This may inform but seems to be a scare tactic to sell his products. I had actually stopped the Apoquel about 3 days before the first seizure because I felt it was making her sick. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. The vet told us anal gland problems can definitely be due to allergies. Heres a handy chart to help you figure out the right dosage for your pup: Mutasim is an author and software engineer from the United States, I and a group of experts made this blog with the aim of answering all the unanswered questions to help as many people as possible. It does seem that the shot and the baytril will make her infection go away and allergies better at least for awhile. He is scheduled for more blood tests and an examination please do not give your pets this drug. He has been on this drug for three years and his allergies are gone. Hoe often do you advise a blood panel be done. Apoquel is a medication that works at the skin level to reduce the mechanism that causes itch. I cannot believe his Dr. gave a medicine that might cause gastro-intestinal problems and suppress the immune system to a puppy that has a weaken immune system from mange and had recent stool and vomiting issues. A typical dose is 1 mg per pound in dogs every 6-8 hours. In fact, the other drugs used for this condition carry similarly disturbing side effects. In some cases, more serious side effects may occur, such as infections or tumors. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. After 2 further doses he went berserk again. Having read a lot of comments on this article I have my own story with Apoquel. Please do not give your dog this medicine I know it makes him stop itching but the outcome is not worth it putting him to sleep, its like putting your child asleep. Our dog is now on a special food do decrease bladder and urinary tract infections. Still sweet and wants to play but, can hardly find the ball when it is right in front of her face. My 7 year old Dachshund was seen my a vet for allergies that caused her ears to itch severly. Today my usually energetic puppy was lethargic vomiting and had extremely runny foul smelling stool (2x). The next morning at 5AM the same thing happened. She sent us to a vet that is a dermatologist 3 hours drive away. Seemingly startled that it happened. Apoquel also isn't recommended for dogs who have serious infections or for dogs who weigh less than 6.6 pounds. My vet put him on apoquel a 5.4 mg dose split in half twice a day. So, your vet will first determine what is causing the problem and treat the underlying issue. this medication is good for a short period of time, but the side affects are far more dangerous, Hello, I have 2 dogs, 45 kg and 8 kg. I also give him on 25mg Benadryl with his food at night. Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. Here are 5 natural alternatives to apoquel for dogs you can try: 1. Is there another page that Im missing. But, Cytopoint isn't a chemical, like most drugs we're familiar with. Replied on 04/19/2011. If you love your dogs please dont give them Apoquel. Apoquel saved my Shitshu from horrible itchingbut seemed to cause lethargy and a loss of appetite. Read all the reviews on this page!! Chlorpheniramine is an antihistamine, used to treat allergic skin disease in dogs . I noticed she had to see alot, but only thought she was marking her spots. His skin is scaley and flakes like crazy. She has been on 3 primary seizure drugs used in humans for almost a year now. The treatment can be very effective. Well I think you know how I feel about this drugIt happened yesterday, I tried chest compressions and CPR and she was gone. One leg even appears lumpy. The chemical messengers which are being blocked by these drugs are involved in more processes than just controlling inflammationmost likely as yet undiscovered!!! Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Metronidazole can have a bitter flavor and so may be best tolerated when given with food. This made a huge difference for surgeries. This is sad. During this time we went back to the vet for guidance and he was put on Prozac for dogs. She is 92# and 4 years old now so she takes 1 1/2 tabs of 16 mg daily. The itching has come back full blown .. bumps swollen paws ect. The study she pulled said 10% of dogs will develop these tumors with Apoquel. I have to admit, I may be the only one in support of Apoquel. Not sure! He was on it 1 week and he started terrible diarhea in my house and outside. Still itching and the straw that broke the camels back was seizures. Two days ago (45 days into Apoquel) Peatie woke from a nap and walked around frantically bumping into things, hes blind, but it seemed more than usual, so I picked him up and he went tight in my armskind of like a dog stretching, but I soon realized he was in a seizure when he urinated all over me. More serious side effects can include coma and apnea. We stopped giving him the poison on the fifth day. Does that sound about right? the only side effects i have noticed is she is happy again. Sounds like these side effevta most are coincidental. So we are finished with it for good. I guess I need to do some more research. We had started a chemotherapy regimen in November which completely zapped her energy. There are a few things to keep in mind when giving your dog either of these medications, however. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Veterinarian, author, advocate for alternative, natural solutions for dog and cat health, Dr. Andrew Jones, DVM He walks daily and plays with is two sisters. The dosage will depends on your dog's weight. Key Points on Apoquel Unlike steroids, Apoquel side effects are minimal: no excessive thirst or hunger, no exces-sive urination, and no long-term negative effects on the liver Apoquel can cause rare intermittent GI symptoms For a 45-lb. Do not use Apoquel in dogs less than 12 months of age or those with serious infections. 5 days later & I still have a very very different dog He went from an extremely confident, friendly & vocal dog who was running round & playing all the time with my other dog into & nervous wreck & he also seems to still have discomfort in his bad leg. BTW, we cleaned up her diet and such, but some of the natural remedies suggested above are almost impossible to administer to my dog. These beneficial bacteria play a role in normalizing the overactive immune system. He had to have the dosage raised today after 2 seizures this morning. The vet put him on Apoquel 16mg a day. This drug works What is hydroxyzine? Took him to the vet today and he has kidney failure. Without that terrible Apoquel. And Univ of Iowa is now under clinical trial for past 4 years. Shame on me for not doing my research. management. I never heard back because the vet told them it wasnt the Apoquil. Full Year 2015 Guidance Updated to Revenue of $4.8 $4.9 Billion and Adjusted Diluted EPS1 of $1.61 $1.68 The rate of adverse events overall was low (<5%) and included Just seems like a lot to me. Our Angel was on prednisone for quite awhile. Due to her age, shes not the best at going outside, but on this pill, she is peeing constantly. I chose to start frequent washing with 3% BPO shampoo to deal with the yeast infections from allergies, (at least thats what the vet told me was causing this). She never did the digging thing previously. I am pretty sure her seizures are tied in with a build up of Apoquel but its impossible to be sure. Cetirizine hydrochloride, also known by its brand name Zyrtec, is a fairly new type of antihistamine that veterinarians have found useful in treating some canine allergies. He is now getting allergy shots and well see how it goes. Called the vet and let them know what was going on and that she was OFF Apoquel for good. It took about 3 months for her red blood cells to start reproducing and return to normal. I will need to confine her if she continues to pee everywhere. The Apoquel was started end of May. I at least know for sure 1 drug I would Never Try and that is this Apoquel. With atopic dermatitis on hepaticlear.. 3 years later camels back was seizures take a look how. 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